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Raspberry Ketones: What the Evidence Says (Very Little)
Raspberry ketones evidence is very thin. Most research is in animals and cells, and the only human studies used multi-ingredient products, so no benefit can be pinned on raspberry ketone alone. In Sugar Defender it is 13th of 22, so a 1 mL serving holds at most 15 mg.
Written by the Sugar Defender label teamUpdated · 4 min read

The compound01
What are raspberry ketones?
Raspberry ketones are the aroma compound that gives red raspberries their scent. Supplements sell a concentrated form, which can be made in a lab.
The label lists "Raspberry Ketones" as the 13th ingredient in the 200 mg blend. It gives no source and no amount.
Raspberry ketones became popular in diet supplements after a wave of online attention, and the buzz ran ahead of the science. Popularity of that kind is easy to confuse with proof, so it helps to ask what was actually tested.
The sales page does not give raspberry ketones an ingredient line of their own, which is worth noting. The ingredient shows up only on the label.
Research02
What does the raspberry ketones evidence show?
It shows very little. Operation Supplement Safety, run by the U.S. Department of Defense, says most research is in animals and cells (OPSS (DoD), Raspberry Ketone).
The only human studies used multi-ingredient products. That means a result cannot be credited to raspberry ketone alone, since the other ingredients could explain it.
The NIH Office of Dietary Supplements agrees that raspberry ketone has only been studied in combination products (NIH ODS, Dietary Supplements for Weight Loss). OPSS adds that no evidence shows these supplements are safe or effective for weight loss.
| Question | Answer |
|---|---|
| Tested alone in people? | No |
| Where most research is | Animals and cells |
| Supplement doses sold | 100 to 1,400 mg a day |
| Safety established? | No |
| Place in Sugar Defender | 13th of 22 |
| Most per 1 mL | 15 mg |
The math03
How much raspberry ketone is in Sugar Defender?
At most 15 mg per 1 mL serving. The label does not print the real figure.
The blend lists parts from most to least by weight (21 CFR 101.36 (eCFR)). The 13th item can hold at most 200 divided by 13, about 15 mg. An even split is about 9 mg.
OPSS says supplement doses run from 100 to 1,400 mg a day, far above normal food intake (OPSS (DoD), Raspberry Ketone). Even the ceiling for this bottle is under a sixth of the low end.
Say a bottle did hold the full 15 mg. That would still be one serving's worth, taken once a day, in a blend of 22 lines. No trial has measured what that does.
That gap cuts two ways. A tiny amount is unlikely to do much, but it also adds little risk. The honest summary is that the line has more to do with a long label than with a dose that matters.
Marketing04
Why do raspberry ketones keep showing up in supplements?
Because the name sounds natural and the weight loss story sells.
Weight loss supplements have a long record of bold claims that regulators later challenged. The FTC says health claims need competent and reliable evidence (FTC, Health Products Compliance Guidance).
A long ingredient list can look impressive. The count of 22 blend ingredients is a fact, not a measure of strength.
- Check whether an amount is printed.
- Ask if the studied dose matches the label.
- Look for a trial of the finished product.
For this bottle, the answers are no, no and no. See the other blend lines page for the rest of the list.
Safety05
Are raspberry ketones safe to take?
Nobody knows for sure. OPSS says no evidence shows that raspberry ketone supplements are safe (OPSS (DoD), Raspberry Ketone).
The label asks pregnant or nursing women, and anyone taking other medication, to consult a physician first. We agree. Unknown safety is a good reason to ask, especially with several other plant extracts in the same bottle.
If you want to lose weight, a plan from your doctor beats an unproven compound. The CDC points to steady loss of 5% to 7% of body weight and 150 minutes of activity a week (CDC, Prediabetes).
The label is typed out on the Sugar Defender supplement facts page.
FAQ06
Raspberry ketone questions
Are raspberry ketones the same as raspberries?
No. Ketones are one aroma compound found in tiny amounts in the fruit. Supplements use a concentrated form, which may be made in a lab, and the dose is far above what raspberries provide.
Is there a clinical trial of raspberry ketones alone?
Not one we can cite. Operation Supplement Safety says the only human studies used products with several ingredients, so no result can be assigned to raspberry ketone by itself.
Where do raspberry ketones sit in the Sugar Defender blend?
Thirteenth of 22 ingredients. Because the label orders them by weight, that position caps the amount at 15 mg per 1 mL serving, though the true amount is not printed.
Who wrote this07
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and the way we check reviews. This website is run by an authorized American Sugar Defender outlet, not by the manufacturer or the distributor. Purchases made through our order links earn us money.
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